9 March 2017 False dyssynchrony: problem with image-based cardiac functional analysis using x-ray computed tomography
Author Affiliations +
We have developed a digitally synthesized patient which we call “Zach” (Zero millisecond Adjustable Clinical Heart) phantom, which allows for an access to the ground truth and assessment of image-based cardiac functional analysis (CFA) using CT images with clinically realistic settings. The study using Zach phantom revealed a major problem with image-based CFA: "False dyssynchrony." Even though the true motion of wall segments is in synchrony, it may appear to be dyssynchrony with the reconstructed cardiac CT images. It is attributed to how cardiac images are reconstructed and how wall locations are updated over cardiac phases. The presence and the degree of false dyssynchrony may vary from scan-to-scan, which could degrade the accuracy and the repeatability (or precision) of image-based CT-CFA exams.
Conference Presentation
© (2017) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Masafumi Kidoh, Masafumi Kidoh, Zeyang Shen, Zeyang Shen, Yuki Suzuki, Yuki Suzuki, Luisa Ciuffo, Luisa Ciuffo, Hiroshi Ashikaga, Hiroshi Ashikaga, George S. K. Fung, George S. K. Fung, Yoshito Otake, Yoshito Otake, Stefan L. Zimmerman, Stefan L. Zimmerman, Joao A. C. Lima, Joao A. C. Lima, Takahiro Higuchi, Takahiro Higuchi, Okkyun Lee, Okkyun Lee, Yoshinobu Sato, Yoshinobu Sato, Lewis C. Becker, Lewis C. Becker, Elliot K. Fishman, Elliot K. Fishman, Katsuyuki Taguchi, Katsuyuki Taguchi, } "False dyssynchrony: problem with image-based cardiac functional analysis using x-ray computed tomography", Proc. SPIE 10132, Medical Imaging 2017: Physics of Medical Imaging, 101321U (9 March 2017); doi: 10.1117/12.2250257; https://doi.org/10.1117/12.2250257

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