9 March 2017 Estimation of breast dose reduction potential for organ-based tube current modulated CT with wide dose reduction arc
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Abstract
This study aimed to estimate the organ dose reduction potential for organ-dose-based tube current modulated (ODM) thoracic CT with wide dose reduction arc. Twenty-one computational anthropomorphic phantoms (XCAT, age range: 27– 75 years, weight range: 52.0-105.8 kg) were used to create a virtual patient population with clinical anatomic variations. For each phantom, two breast tissue compositions were simulated: 50/50 and 20/80 (glandular-to-adipose ratio). A validated Monte Carlo program was used to estimate the organ dose for standard tube current modulation (TCM) (SmartmA, GE Healthcare) and ODM (GE Healthcare) for a commercial CT scanner (Revolution, GE Healthcare) with explicitly modeled tube current modulation profile, scanner geometry, bowtie filtration, and source spectrum. Organ dose was determined using a typical clinical thoracic CT protocol. Both organ dose and CTDIvol-to-organ dose conversion coefficients (h factors) were compared between TCM and ODM. ODM significantly reduced all radiosensitive organ doses (p<0.01). The breast dose was reduced by 30±2%. For h factors, organs in the anterior region (e.g. thyroid, stomach) exhibited substantial decreases, and the medial, distributed, and posterior region either saw an increase or no significant change. The organ-dose-based tube current modulation significantly reduced organ doses especially for radiosensitive superficial anterior organs such as the breasts.
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Wanyi Fu, Wanyi Fu, Gregory M. Sturgeon, Gregory M. Sturgeon, Greeshma Agasthya, Greeshma Agasthya, W. Paul Segars, W. Paul Segars, Anuj J. Kapadia, Anuj J. Kapadia, Ehsan Samei, Ehsan Samei, } "Estimation of breast dose reduction potential for organ-based tube current modulated CT with wide dose reduction arc", Proc. SPIE 10132, Medical Imaging 2017: Physics of Medical Imaging, 1013246 (9 March 2017); doi: 10.1117/12.2255797; https://doi.org/10.1117/12.2255797
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