9 March 2017 Contrast-enhanced spectral mammography based on a photon-counting detector: quantitative accuracy and radiation dose
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Abstract
Contrast-enhanced mammography has been used to demonstrate functional information about a breast tumor by injecting contrast agents. However, a conventional technique with a single exposure degrades the efficiency of tumor detection due to structure overlapping. Dual-energy techniques with energy-integrating detectors (EIDs) also cause an increase of radiation dose and an inaccuracy of material decomposition due to the limitations of EIDs. On the other hands, spectral mammography with photon-counting detectors (PCDs) is able to resolve the issues induced by the conventional technique and EIDs using their energy-discrimination capabilities. In this study, the contrast-enhanced spectral mammography based on a PCD was implemented by using a polychromatic dual-energy model, and the proposed technique was compared with the dual-energy technique with an EID in terms of quantitative accuracy and radiation dose. The results showed that the proposed technique improved the quantitative accuracy as well as reduced radiation dose comparing to the dual-energy technique with an EID. The quantitative accuracy of the contrast-enhanced spectral mammography based on a PCD was slightly improved as a function of radiation dose. Therefore, the contrast-enhanced spectral mammography based on a PCD is able to provide useful information for detecting breast tumors and improving diagnostic accuracy.
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Seungwan Lee, Sooncheol Kang, Jisoo Eom, "Contrast-enhanced spectral mammography based on a photon-counting detector: quantitative accuracy and radiation dose", Proc. SPIE 10132, Medical Imaging 2017: Physics of Medical Imaging, 1013248 (9 March 2017); doi: 10.1117/12.2253591; https://doi.org/10.1117/12.2253591
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