High resolution laboratory grating-based x-ray phase-contrast CT

Manuel P. Viermetz; Lorenz J. B. Birnbacher; Andreas Fehringer; Marian Willner; Peter B. Noel; Franz Pfeiffer; Julia Herzen

doi:10.1117/12.2255657

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9 March 2017 High resolution laboratory grating-based x-ray phase-contrast CT

Manuel P. Viermetz; Lorenz J. B. Birnbacher; Andreas Fehringer; Marian Willner; Peter B. Noel; Franz Pfeiffer; Julia Herzen

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Proceedings Volume 10132, Medical Imaging 2017: Physics of Medical Imaging; 101325K (2017) https://doi.org/10.1117/12.2255657
Event: SPIE Medical Imaging, 2017, Orlando, Florida, United States

Abstract

Grating-based phase-contrast computed tomography (gbPC-CT) is a promising imaging method for imaging of soft tissue contrast without the need of any contrast agent. The focus of this study is the increase in spatial resolution without loss in sensitivity to allow visualization of pathologies comparable to the convincing results obtained at the synchrotron. To improve the effective pixel size a super-resolution reconstruction based on subpixel shifts involving a deconvolution of the image is applied on differential phase-contrast data. In our study we could achieve an effective pixel sizes of 28mm without any drawback in terms of sensitivity or the ability to measure quantitative data.

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Manuel P. Viermetz, Lorenz J. B. Birnbacher, Andreas Fehringer, Marian Willner, Peter B. Noel, Franz Pfeiffer, and Julia Herzen "High resolution laboratory grating-based x-ray phase-contrast CT", Proc. SPIE 10132, Medical Imaging 2017: Physics of Medical Imaging, 101325K (9 March 2017); https://doi.org/10.1117/12.2255657

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