13 March 2017 Ultrasound tomography imaging with waveform sound speed: parenchymal changes in women undergoing tamoxifen therapy
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Abstract
Ultrasound tomography (UST) is an emerging modality that can offer quantitative measurements of breast density. Recent breakthroughs in UST image reconstruction involve the use of a waveform reconstruction as opposed to a raybased reconstruction. The sound speed (SS) images that are created using the waveform reconstruction have a much higher image quality. These waveform images offer improved resolution and contrasts between regions of dense and fatty tissues. As part of a study that was designed to assess breast density changes using UST sound speed imaging among women undergoing tamoxifen therapy, UST waveform sound speed images were then reconstructed for a subset of participants. These initial results show that changes to the parenchymal tissue can more clearly be visualized when using the waveform sound speed images. Additional quantitative testing of the waveform images was also started to test the hypothesis that waveform sound speed images are a more robust measure of breast density than ray-based reconstructions. Further analysis is still needed to better understand how tamoxifen affects breast tissue.
Conference Presentation
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Mark Sak, Neb Duric, Peter Littrup, Mark Sherman, Gretchen Gierach, "Ultrasound tomography imaging with waveform sound speed: parenchymal changes in women undergoing tamoxifen therapy", Proc. SPIE 10139, Medical Imaging 2017: Ultrasonic Imaging and Tomography, 101390W (13 March 2017); doi: 10.1117/12.2254472; https://doi.org/10.1117/12.2254472
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