15 March 2017 Estimating cardiac fiber orientations in pig hearts using registered ultrasound and MR image volumes
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Heart fiber mechanics can be important predictors in current and future cardiac function. Accurate knowledge of these mechanics could enable cardiologists to provide a diagnosis before conditions progress. Magnetic resonance diffusion tensor imaging (MR-DTI) has been used to determine cardiac fiber orientations. Ultrasound is capable of providing anatomical information in real time, enabling a physician to quickly adjust parameters to optimize image scans. If known fiber orientations from a template heart measured using DTI can be accurately deformed onto a cardiac ultrasound volume, fiber orientations could be estimated for the patient without the need for a costly MR scan while still providing cardiologists valuable information about the heart mechanics. In this study, we apply the method to pig hearts, which are a close representation of human heart anatomy. Experiments from pig hearts show that the registration method achieved an average Dice similarity coefficient (DSC) of 0.819 ± 0.050 between the ultrasound and deformed MR volumes and that the proposed ultrasound-based method is able to estimate the cardiac fiber orientation in pig hearts.
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James D. Dormer, James D. Dormer, Yuguang Meng, Yuguang Meng, Xiaodong Zhang, Xiaodong Zhang, Rong Jiang, Rong Jiang, Mary B. Wagner, Mary B. Wagner, Baowei Fei, Baowei Fei, } "Estimating cardiac fiber orientations in pig hearts using registered ultrasound and MR image volumes", Proc. SPIE 10139, Medical Imaging 2017: Ultrasonic Imaging and Tomography, 101391G (15 March 2017); doi: 10.1117/12.2255515; https://doi.org/10.1117/12.2255515

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