1 March 2017 Applications of QCL mid-IR imaging to the advancement of pathology
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Abstract
Quantum Cascade Laser (QCL) spectroscopic imaging is a novel technique with many potential applications to histopathology. Like traditional Fourier Transform Infrared (FT-IR) imaging, QCL spectroscopic imaging derives biochemical data coupled to the spatial information of a tissue sample, and can be used to improve the diagnostic and prognostic value of assessment of a tissue biopsy. This technique also offers advantages over traditional FT-IR imaging, specifically the capacity for discrete frequency and real-time imaging. In this work we present applications of QCL spectroscopic imaging to tissue samples, including discrete frequency imaging, to compare with FT-IR and its potential value to pathology.
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Hari Sreedhar, Vishal K. Varma, Benjamin Bird, Grace Guzman, Michael J. Walsh, "Applications of QCL mid-IR imaging to the advancement of pathology", Proc. SPIE 10140, Medical Imaging 2017: Digital Pathology, 1014004 (1 March 2017); doi: 10.1117/12.2254523; https://doi.org/10.1117/12.2254523
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