Changes in optical properties of biological tissue: experiment and Monte Carlo simulation

Pavel Kaspar; Elena Prokopyeva; Pavel Tománek; Lubomír Grmela

doi:10.1117/12.2263271

23 December 2016 Changes in optical properties of biological tissue: experiment and Monte Carlo simulation

Pavel Kaspar, Elena Prokopyeva, Pavel Tománek, Lubomír Grmela

Proceedings Volume 10142, 20th Slovak-Czech-Polish Optical Conference on Wave and Quantum Aspects of Contemporary Optics; 101420R (2016) https://doi.org/10.1117/12.2263271
Event: 20th Slovak-Czech-Polish Optical Conference on Wave and Quantum Aspects of Contemporary Optics, 2016, Jasna, Slovakia

Abstract

Biological tissue is a very complex, yet important material to describe and analyze. Its properties are affected by chemical processes too numerous to easily understand and describe. By simplifying and grouping some aspects together we are able to create a model for simulating behavior of a photon inside of a biological sample. Using the Monte Carlo method an algorithm for calculating photon propagation through the tissue based on several optical parameters, like absorption and scattering coefficients, refractive indices and optical anisotropy, can be created. Based on some of the results of the simulation a comparative measurement on a muscle sample was performed to prove the usefulness of such model and to describe changes in the tissue sample based on the aforementioned optical parameters in both real life and the simulation.

Citation Download Citation

Pavel Kaspar, Elena Prokopyeva, Pavel Tománek, and Lubomír Grmela "Changes in optical properties of biological tissue: experiment and Monte Carlo simulation", Proc. SPIE 10142, 20th Slovak-Czech-Polish Optical Conference on Wave and Quantum Aspects of Contemporary Optics, 101420R (23 December 2016); https://doi.org/10.1117/12.2263271

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KEYWORDS

Tissue optics

Monte Carlo methods

Scattering

Absorption

Anisotropy

Sensors

Optical properties

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