The need to exchange data wirelessly has increased as the growth of the number of mobile devices. Visible light communication (VLC) is a promising technology to alleviate the growing traffic problem. However, the occlusion problem is a difficulty in VLC system. In order to solve the problem, an anti-occlusion VLC system has been proposed in this article. In this VLC system, we propose the channel cooperative selection mechanism, which is based on the best-response dynamics and best response strategies of the game theory. This mechanism uses bit error ratio (BER) as the utility function to optimize system performance. In addition, the system provides three candidate communication channels, including direct channel, indirect channel, and mixed channel, to active users who will select the optimal communication channel. Moreover, the anti-occlusion VLC system has many application scenarios, such as the office, which has practical significance. For verifying the validity of the proposed mechanism, we accomplish the simulation results in terms of BER and throughput in different communication cases. It is demonstrated that the proposed channel cooperative selection mechanism in VLC systems offers superior performance in environment of obstructions.