Motivated by potential benefits such as sensor user-friendly, multiplexing capabilities and high sensitivities, nanophotonic lab-on-chip biosensors have profiled themselves as an excellent alternative to traditional analytical techniques. Modern diagnostics is demanding novel analytical tools that could enable quick, accurate, sensitive, reliable and cost-effective results so that appropriate treatments or remediantion actions can be implemented in time, leading to improved outcomes.
The main objective of our research is to achieve such ultrasensitive platforms for label-free analysis using nanophotonic technologies and custom-designed biofunctionalization protocols, accomplishing the requirements of disposability and portability. We are using innovative designs of nanophotonic biosensors based silicon photonics technology (nanointerferometers) and full microfluidics lab-on-chip integration. We have demonstrated the suitability of the photonic nanobiosensors for the detection, with extremely sensitivity and selectivity, of marine pollutants and human disease biomarkers. In all cases, our sensing methodology has shown excellent robustness with high reproducibility and sensitivity, rendering in valuable tool for the fast diagnostics of un-treated bodily fluids or environmental samples.