Estimation of the quantum efficiency of the photodissociation of HbO2 and HbCO

A. I. Gisbrecht; S. A. Mamilov; S. S. Esman; M. M. Asimov

doi:10.1117/12.2261829

5 January 2017 Estimation of the quantum efficiency of the photodissociation of HbO₂ and HbCO

A. I. Gisbrecht, S. A. Mamilov, S. S. Esman, M. M. Asimov

Proceedings Volume 10226, 19th International Conference and School on Quantum Electronics: Laser Physics and Applications; 1022619 (2017) https://doi.org/10.1117/12.2261829
Event: International Conference and School on Quantum Electronics "Laser Physics and Applications" - ICSQE 2016, 2016, Sozopol, Bulgaria

Abstract

The paper presents our results on the study of the efficiency of inter-fractional changes in hemoglobin molecules depending on the laser radiation parameters. The evaluation of the quantum efficiency of light interaction in vivo with oxyhemoglobin (HbO2) and carboxyhemoglobin (HbCO) in the blood at wavelengths for 525 and 605 nm is presented. The photodissociation yield of 11% for HbO₂ and 79% for HbCO are measured at the wavelength of 525 nm and 10 % for HbO₂ and 76 % for HbCO at a wavelength of 605 nm. Thus, the quantum yield of photodissociation of the HbCO is considerably higher, which ensures high efficiency of photodecomposition of the HbCO in the blood. The obtained results can be used in the clinical phototherapy practice for effective treatment of CO poisoning.

Citation Download Citation

A. I. Gisbrecht, S. A. Mamilov, S. S. Esman, and M. M. Asimov "Estimation of the quantum efficiency of the photodissociation of HbO₂ and HbCO", Proc. SPIE 10226, 19th International Conference and School on Quantum Electronics: Laser Physics and Applications, 1022619 (5 January 2017); https://doi.org/10.1117/12.2261829

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