7 June 2017 On the potential of laser driven isotope generation at ELI-NP for positron emission tomography
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The huge progress made in the laser driven ion acceleration had open the possibility of using ions generated in high power laser interactions with solid targets for the production of medical isotopes. Indeed, lasers could provide several key features with respect to the traditional method where the target activation is produced by particle beams delivered by cyclotrons. The price and the dimensions of high power lasers are on a descendant slope and the quality of the produced ion beams is continuously increasing. However, in order to compete with cyclotrons, the average proton current intensity has to be increased for example by increasing the frequency of the laser pulses. In our contribution, we review the general ideas of the laser-based radioisotope production and we present our analysis on the potential of the medical isotope generation at ELI-NP with a focus on 18F. We use estimations of the proton beam parameters and a code implemented in Geant4 for computing the yield of the main production channel taking into account the experimental conditions available soon at ELI-NP. The obtained results are compatible with previous studies and will be verified by experiments foreseen at the future ELI-NP facility, under construction now in Magurele, Romania.
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A. S. Cucoanes, A. S. Cucoanes, D. L. Balabanski, D. L. Balabanski, F. Canova, F. Canova, P. Cuong, P. Cuong, F. Negoita, F. Negoita, F. Puicea, F. Puicea, K. A. Tanaka, K. A. Tanaka, } "On the potential of laser driven isotope generation at ELI-NP for positron emission tomography", Proc. SPIE 10239, Medical Applications of Laser-Generated Beams of Particles IV: Review of Progress and Strategies for the Future, 102390B (7 June 2017); doi: 10.1117/12.2273769; https://doi.org/10.1117/12.2273769

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