Noninvasive imaging of oral mucosae with optical coherence tomography

Cheng-Yu Lee; Wei-Chuan Chen; Meng-Tsan Tsai

doi:10.1117/12.2269384

18 April 2017 Noninvasive imaging of oral mucosae with optical coherence tomography

Cheng-Yu Lee, Wei-Chuan Chen, Meng-Tsan Tsai

Proceedings Volume 10251, Biomedical Imaging and Sensing Conference; 102511E (2017) https://doi.org/10.1117/12.2269384
Event: SPIE Technologies and Applications of Structured Light, 2017, Yokohama, Japan

Abstract

In this study, a swept-source optical coherence tomography (OCT) system is developed for in vivo visualization of structural and vascular morphology oral mucosa. For simplification of optical probe fabrication, probe weight, and system setup, the body of the scanning probe is fabricated by a 3D printer to fix the optical components and the mechanical scanning device, and a partially reflective slide is attached at the output end of probe to achieve a common-path configuration. Aside from providing the ability of 3D structural imaging with the developed system, 3D vascular images of oral mucosa can be simultaneously obtained. Then, different locations of oral mucosa are scanned with common-path OCT. The results show that epithelium and lamina propria layers as well as fungiform papilla can be identified and microvascular images can be acquired. With the proposed probe, the system cost and volume can be greatly reduced. Experimental results indicate that such common-path OCT system could be further implemented for oral cancer diagnosis.

Citation Download Citation

Cheng-Yu Lee, Wei-Chuan Chen, and Meng-Tsan Tsai "Noninvasive imaging of oral mucosae with optical coherence tomography", Proc. SPIE 10251, Biomedical Imaging and Sensing Conference, 102511E (18 April 2017); https://doi.org/10.1117/12.2269384

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