18 April 2017 Macroscopic assembly by optical control of zmol-level DNA hybridization
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Proceedings Volume 10252, Optical Manipulation Conference; 102520J (2017) https://doi.org/10.1117/12.2275108
Event: SPIE Technologies and Applications of Structured Light, 2017, Yokohama, Japan
Abstract
Remote acceleration of a molecular recognition will open an avenue for the control of various biological functions. Here, we have developed a new principle for the rapid macroscopic assembly based on the light-induced molecular recognition via nanoparticles. Remarkably, as an application of this principle, we have demonstrated the submillimetre network formation triggered by light-induced hybridization of zmol-level DNA within a few minutes. This finding will be used for the rapid and highly sensitive genetic screening without fluorescent labeling.
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Takuya Iida, Yushi Nishimura, Mamoru Tamura, Keisuke Nishida, Syoji Ito, Shiho Tokonami, "Macroscopic assembly by optical control of zmol-level DNA hybridization", Proc. SPIE 10252, Optical Manipulation Conference, 102520J (18 April 2017); doi: 10.1117/12.2275108; https://doi.org/10.1117/12.2275108
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