Non-oxide glasses1-5 find an increasing use in fiber optic applications. Most of the current research activity is in the halide glass fibers used as active hosts for rare-earth ion doping. These include, 1.3 and 1.5 μm optical amplifiers, frequency upconversion devices, fiber lasers, permanent gratings, etc. Other non-oxide glasses, chalcogenides and mixed chalcogenide halide glasses have potential in fiber applications in IR laser power deliverers, image-guides and sensors. Some of the important issues that require further research include, the glass purification, stable glass compositions, hermetic coatings for fibers, better methods for preform and fiber fabrication.