Axial length variation impacts on retinal vessel density and foveal avascular zone area measurement using optical coherence tomography angiography

Danuta M. Sampson; Peijun Gong; Di An; Moreno Menghini; Alex Hansen; David A. Mackey; David D Sampson; Fred K Chen

doi:10.1117/12.2270134

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29 April 2017 Axial length variation impacts on retinal vessel density and foveal avascular zone area measurement using optical coherence tomography angiography

Danuta M. Sampson, Peijun Gong, Di An, Moreno Menghini, Alex Hansen, David A. Mackey, David D Sampson, Fred K Chen

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Proceedings Volume 10340, International Conference on Biophotonics V; 1034017 (2017) https://doi.org/10.1117/12.2270134
Event: International Conference on Biophotonics V, 2017, Perth, Australia

Abstract

We examined the impact of axial length on superficial retinal vessel density (SRVD) and foveal avascular zone area (FAZA) measurement using optical coherence tomography angiography. The SRVD and FAZA were quantified before and after correction for magnification error associated with axial length variation. Although SRVD did not differ before and after correction for magnification error in the parafoveal region, change in foveal SRVD and FAZA were significant. This has implications for clinical trials outcome in diseased eyes where significant capillary dropout may occur in the parafovea.

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Danuta M. Sampson, Peijun Gong, Di An, Moreno Menghini, Alex Hansen, David A. Mackey, David D Sampson, and Fred K Chen "Axial length variation impacts on retinal vessel density and foveal avascular zone area measurement using optical coherence tomography angiography", Proc. SPIE 10340, International Conference on Biophotonics V, 1034017 (29 April 2017); https://doi.org/10.1117/12.2270134

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