7 September 2017 Effects of cations and cholesterol with sphingomyelin membranes investigated by high-resolution broadband sum frequency vibrational spectroscopy
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Abstract
Sphingomyelin(SM) is specifically enriched in the plasma membrane of mammalian cells. Its molecular structure is compose by N-acyl-Derythro-sphingosylphosphorylcholine. The function of the SM related to membrane signaling and protein trafficking are relied on the interactions of the SM, cations, cholesterol and proteins. In this report, the interaction of three different nature SMs, cations and cholesterol at air/aqueous interfaces studied by high-resolution broadband sum frequency vibrational spectroscopy, respectively. Our results shed lights on understanding the relationship between SMs monolayer, cholesterol and Cations.
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Zhen Zhang, Rong-juan Feng, Yi-yi Li, Ming-hua Liu, Yuan Guo, "Effects of cations and cholesterol with sphingomyelin membranes investigated by high-resolution broadband sum frequency vibrational spectroscopy", Proc. SPIE 10380, Ultrafast Nonlinear Imaging and Spectroscopy V, 1038002 (7 September 2017); doi: 10.1117/12.2273017; https://doi.org/10.1117/12.2273017
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