28 July 2017 Delayed luminescence in a multiparameter approach to evaluation and reduction of radiobiological risks
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Abstract
In the framework of the research project ETHICS “Pre-clinical experimental and theoretical studies to improve treatment and protection by charged particles” funded by the National Nuclear Physics Institute, Italy, we studied the phenomenon called delayed luminescence emitted by non-tumorigenic breast epithelial MCF10A cell line after proton irradiation at different doses (0.5, 2, 6, 9 Gy). The aim is to found possible correlations between delayed luminescence and in vitro damaging induced by ion irradiation. The first results of this research show that the delayed luminescence kinetics is proton dose dependent. An interesting correlation between delayed luminescence and clonogenic potential was observed.
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Rosaria Grasso, Rosaria Grasso, Francesco Paolo Cammarata, Francesco Paolo Cammarata, Luigi Minafra, Luigi Minafra, Valentina Marchese, Valentina Marchese, Giorgio Russo, Giorgio Russo, Lorenzo Manti, Lorenzo Manti, Francesco Musumeci, Francesco Musumeci, Agata Scordino, Agata Scordino, } "Delayed luminescence in a multiparameter approach to evaluation and reduction of radiobiological risks ", Proc. SPIE 10413, Novel Biophotonics Techniques and Applications IV, 104130L (28 July 2017); doi: 10.1117/12.2285851; https://doi.org/10.1117/12.2285851
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