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Digital holographic microscopy (DHM) was used as multimodal optical method for nanomaterial toxicity testing that overcomes the limitations and assay disturbances of conventional in vitro assays based on absorbance or fluorescence read outs.
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Sarah Mues, Steffi Ketelhut, Björn Kemper, Jürgen Schnekenburger, "Digital holographic microscopy as multimodal read out for in vitro nanomaterial cytotoxicity testing," Proc. SPIE 10414, Advances in Microscopic Imaging, 104140J (28 July 2017); https://doi.org/10.1117/12.2287269