1 August 2017 Light and ultrasound activated microbubbles around gold nanorods for photoacoustic microsurgery
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Abstract
Photoacoustic imaging and microsurgery have recently attracted attention for applications in oncology. Here, we present a versatile set-up to trigger vapor microbubbles around plasmonic nanoparticles by a combined light-ultrasound excitation. This system enables the detection and parametrization of bubbles as a function of several variables, such us optical fluence, ultrasound intensity, nanoparticles concentration, thus providing useful directions to the development of new strategies for treatments based on optical cavitation.
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Lucia Cavigli, Lucia Cavigli, Sonia Centi, Sonia Centi, Sarah Lai, Sarah Lai, Claudia Borri, Claudia Borri, Filippo Micheletti, Filippo Micheletti, Paolo Tortoli, Paolo Tortoli, Ilaria Panettieri, Ilaria Panettieri, Ingolf Streit, Ingolf Streit, Francesca Rossi, Francesca Rossi, Fulvio Ratto, Fulvio Ratto, Roberto Pini, Roberto Pini, } "Light and ultrasound activated microbubbles around gold nanorods for photoacoustic microsurgery", Proc. SPIE 10415, Opto-Acoustic Methods and Applications in Biophotonics III, 1041504 (1 August 2017); doi: 10.1117/12.2286055; https://doi.org/10.1117/12.2286055
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