1 August 2017 Gold nanoparticle-mediated laser stimulation causes a complex stress signal in neuronal cells
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Abstract
Gold nanoparticle mediated laser stimulation of neuronal cells allows for cell activation on a single-cell level. It could therefore be considered an alternative to classical electric neurostimulation. The physiological impact of this new approach has not been intensively studied so far. Here, we investigate the targeted cell’s reaction to a laser stimulus based on its calcium response. A complex cellular reaction involving multiple sources has been revealed.
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Sonja Johannsmeier, Sonja Johannsmeier, Patrick Heeger, Patrick Heeger, Mitsuhiro Terakawa, Mitsuhiro Terakawa, Stefan Kalies, Stefan Kalies, Alexander Heisterkamp, Alexander Heisterkamp, Tammo Ripken, Tammo Ripken, Dag Heinemann, Dag Heinemann, } "Gold nanoparticle-mediated laser stimulation causes a complex stress signal in neuronal cells", Proc. SPIE 10417, Medical Laser Applications and Laser-Tissue Interactions VIII, 104170B (1 August 2017); doi: 10.1117/12.2284174; https://doi.org/10.1117/12.2284174
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