7 August 2017 In-vivo monitoring of oxygen saturation in murine carcinoma during PDT by diode laser light diffuse reflectance
Author Affiliations +
Proceedings Volume 10445, Photonics Applications in Astronomy, Communications, Industry, and High Energy Physics Experiments 2017; 104453N (2017) https://doi.org/10.1117/12.2280980
Event: Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2017, 2017, Wilga, Poland
Abstract
In the paper we explored the possibility of monitoring oxygenation of the tumor tissue through the registration of light diffuse reflectance. This method can also be helpful for assessment the effectiveness of PDT, defining the level of vascular damage and the degree of the tumor oxygenation. We also propose the modification of PDT procedure by using a modulated laser that enables to better maintain the necessary parameters for the PS activation and oxygen generation in irradiated tissues simultaneously allowing to reduce the light dose required for tumor treatment.
© (2017) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Vladimir V. Kholin, Oksana M. Chepurna, Irina O. Shton, Valerii S. Voytsehovich, Sergii V. Pavlov, Natalia I. Zabolotna, Ryszard Romaniuk, Waldemar Wójcik, Yedilkhan Amirgaliyev, Vladimir Kovalev, "In-vivo monitoring of oxygen saturation in murine carcinoma during PDT by diode laser light diffuse reflectance", Proc. SPIE 10445, Photonics Applications in Astronomy, Communications, Industry, and High Energy Physics Experiments 2017, 104453N (7 August 2017); doi: 10.1117/12.2280980; https://doi.org/10.1117/12.2280980
PROCEEDINGS
6 PAGES


SHARE
Back to Top