14 February 2018 Catheter design optimization for practical intravascular photoacoustic imaging (IVPA) of vulnerable plaques
Author Affiliations +
Abstract
Intravascular photoacoustic/ultrasound imaging (IVPA/US) can image the structure and composition of atherosclerotic lesions identifying lipid-rich plaques ex vivo and in vivo. In the literature, multiple IVPA/US catheter designs were presented and validated both in ex-vivo models and preclinical in-vivo situations. Since the catheter is a critical component of the imaging system, we discuss here a catheter design oriented to imaging plaque in a realistic and translatable setting. We present a catheter optimized for light delivery, manageable flush parameters and robustness with reduced mechanical damage risks at the laser/catheter joint interface. We also show capability of imaging within sheath and in water medium.
© (2018) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Sophinese Iskander-Rizk, Min Wu, Geert Springeling, Frits Mastik, Robert H. S. H. Beurskens, Antonius F. W. van der Steen, Gijs van Soest, "Catheter design optimization for practical intravascular photoacoustic imaging (IVPA) of vulnerable plaques", Proc. SPIE 10471, Diagnostic and Therapeutic Applications of Light in Cardiology 2018, 1047111 (14 February 2018); doi: 10.1117/12.2287364; https://doi.org/10.1117/12.2287364
PROCEEDINGS
8 PAGES


SHARE
Back to Top