[Ru(bipy)3]2+ nanoparticle-incorporate dental light cure resin to promote photobiomodulation therapy for enhanced vital pulp tissue repair

Rodrigo C. Mosca; Nicholas Young; Carlos A. Zeituni; Praveen R. Arany D.D.S.

doi:10.1117/12.2290719

23 March 2018 [Ru(bipy)₃]²⁺ nanoparticle-incorporate dental light cure resin to promote photobiomodulation therapy for enhanced vital pulp tissue repair

Rodrigo C. Mosca, Nicholas Young, Carlos A. Zeituni, Praveen R. Arany D.D.S.

Author Affiliations +

Proceedings Volume 10477, Mechanisms of Photobiomodulation Therapy XIII; 104770T (2018) https://doi.org/10.1117/12.2290719
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

The use of nanoparticle on dental light cure resin is not new, currently several compounds (nanoadditives) are used to promote better communication between the restorative material and biological tissues. The interest for this application is growing up to enhance mechanical proprieties to dental tissue cells regeneration. Bioactive nanoparticles and complex compounds with multiple functions are the major target for optimizing the restorative materials. In this work, we incorporate [Ru(bipy)₃]²⁺ nanoparticles, that absorbs energy at 450 nm (blue-light) and emits strongly at ~620 nm (red-light), in PLGA Microspheres and insert it in Dental Light Cure Resin to promote the Photobiomodulation Therapy (PBM) effects to accelerate dental pulp repair by in vitro using cytotoxicity and proliferation assay.

Citation Download Citation

Rodrigo C. Mosca, Nicholas Young, Carlos A. Zeituni, and Praveen R. Arany D.D.S. "[Ru(bipy)₃]²⁺ nanoparticle-incorporate dental light cure resin to promote photobiomodulation therapy for enhanced vital pulp tissue repair", Proc. SPIE 10477, Mechanisms of Photobiomodulation Therapy XIII, 104770T (23 March 2018); https://doi.org/10.1117/12.2290719

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