1 March 2018 Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model
Author Affiliations +
Abstract
Specific tumor targeting can result in selective labeling of cancer in vivo for surgical navigation. In the present study, we show that the use of an anti-CEA antibody conjugated to the near-infrared (NIR) fluorescent dye, IRDye800CW, can selectively target and label pancreatic cancer and its metastases in a clinically relevant patient derived xenograft mouse model.
Conference Presentation
© (2018) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Thinzar M. Lwin, Kentaro Miyake, Takashi Murakami, Jonathan C. DeLong, Paul J. Yazaki, John E. Shivley, Bryan Clary, Robert M. Hoffman, Michael Bouvet, "Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model", Proc. SPIE 10478, Molecular-Guided Surgery: Molecules, Devices, and Applications IV, 104780O (1 March 2018); doi: 10.1117/12.2292546; https://doi.org/10.1117/12.2292546
PROCEEDINGS
10 PAGES + PRESENTATION

SHARE
Back to Top