8 February 2018 Optical mapping of the brain activity in children with Down's syndrome
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Down’s syndrome (DS) has been shown to be associated with many neurological complications, including cognitive deficits, seizures, early-onset dementia that resembles Alzheimer’s disease, and neurological complications of systemic disorders. DS patients show to have poor performance in executive functions (EF) and fine motor skills. In this study, we examined the brain hemodynamic responses and brain activation patterns of DS children during the completion of EF tasks. Revealing its neural mechanism of DS is not only able to contribute to the early intervention of this children with DS, but also increase understanding of developmental cascades in childhood.
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Zhen Yuan, Zhen Yuan, Fengmei Lu, Fengmei Lu, } "Optical mapping of the brain activity in children with Down's syndrome", Proc. SPIE 10480, Clinical and Translational Neurophotonics 2018, 1048009 (8 February 2018); doi: 10.1117/12.2286795; https://doi.org/10.1117/12.2286795

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