8 February 2018 Creation of an optically tunable, solid tissue phantom for use in cancer detection
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Abstract
An optically tunable, solid tissue phantom was developed in order to aid in the verification and validation of non-destructive cancer detection technologies based on fluorescence spectroscopy. The solid tissue phantom contained agarose, hemoglobin, Intralipid, NADH, and FAD. The redox ratio of the solid phantoms were shown to be tunable; thus, indicating that these phantoms could be used to tailor specific optical conditions that mimic cancerous and healthy tissues. Therefore, this solid tissue phantom can serve as a suitable test bed to evaluate fluorescence spectroscopy based cancer detection devices.
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Matthew B. Tucker, Matthew B. Tucker, Catherine Wallace, Catherine Wallace, Sreekar Mantena, Sreekar Mantena, Neil Cornwell, Neil Cornwell, Weston Ross, Weston Ross, Ren Odion, Ren Odion, Tuan Vo-Dinh, Tuan Vo-Dinh, Patrick Codd, Patrick Codd, } "Creation of an optically tunable, solid tissue phantom for use in cancer detection", Proc. SPIE 10480, Clinical and Translational Neurophotonics 2018, 104800H (8 February 2018); doi: 10.1117/12.2290499; https://doi.org/10.1117/12.2290499
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