14 February 2018 Ophthalmic laser system integrated with speckle variance optical coherence tomography for real-time temperature monitoring
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Abstract
A commercial ophthalmic laser system (R;GEN, Lutronic Corp) was integrated with a swept-source optical coherence tomography (OCT) imaging system for real-time tissue temperature monitoring. M-scan OCT images were acquired during laser-pulse radiation, and speckle variance OCT (svOCT) images were analyzed to deduce temporal signal variations related to tissue temperature change from laser-pulse radiation. A phantom study shows that svOCT magnitude increases abruptly after laser pulse radiation and recovered exponentially, and the peak intensity of svOCT image was linearly dependent on pulse laser energy until it saturates. A study using bovine iris also showed signal variation dependence on the laser pulse radiation, and the variation was more distinctive with higher energy level.
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Soohyun Lee, Soohyun Lee, Changho Lee, Changho Lee, Gyeongwoo Cheon, Gyeongwoo Cheon, Jongmin Kim, Jongmin Kim, Dongki Jo, Dongki Jo, Jihoon Lee, Jihoon Lee, Jin U. Kang, Jin U. Kang, } "Ophthalmic laser system integrated with speckle variance optical coherence tomography for real-time temperature monitoring", Proc. SPIE 10483, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXII, 104832C (14 February 2018); doi: 10.1117/12.2291183; https://doi.org/10.1117/12.2291183
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