14 February 2018 Wide field-of-view high lateral resolution optical coherence tomography with 3D image stitching and superresolution
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Abstract
We report that wide field-of-view (FOV) optical coherence tomography images with high lateral resolution can be obtained by using superresolution and 3D image stitching techniques. About 3 times lateral resolution improvement from 6.20 μm to 2.19 μm using a focusing lens of 0.08 numerical aperture has been demonstrated. With such lens the FOV is generally small owing to off-axis focusing degradation. To enlarge the FOV while maintaining high lateral resolution, 3D image stitching technique is introduced to effectively reconstruct an ultra-wide FOV 3D image of 2.10x1.15 mm2 lateral area from ten C-scans of 500×500 μm2 FOV. Improved FOV with high lateral resolution should benefit various biomedical imaging applications.
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Kai Shen, Kai Shen, Sarfaraz Baig, Sarfaraz Baig, Guomin Jiang, Guomin Jiang, Michael R. Wang, Michael R. Wang, } "Wide field-of-view high lateral resolution optical coherence tomography with 3D image stitching and superresolution", Proc. SPIE 10483, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXII, 104832R (14 February 2018); doi: 10.1117/12.2287480; https://doi.org/10.1117/12.2287480
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