19 February 2018 hyperspectral characterization of tissue simulating phantoms using a supercontinuum laser in a spatial frequency domain imaging instrument
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Abstract
Hyperspectral Imaging (HSI) is a growing field in tissue optics due to its ability to collect continuous spectral features of a sample without a contact probe. Spatial Frequency Domain Imaging (SFDI) is a non-contact wide-field spectral imaging technique that is used to quantitatively characterize tissue structure and chromophore concentration. In this study, we designed a Hyperspectral SFDI (H-SFDI) instrument which integrated a supercontinuum laser source to a wavelength tuning optical configuration and a sCMOS camera to extract spatial (Field of View: 2cm×2cm) and broadband spectral features (580nm-950nm). A preliminary experiment was also performed to integrate the hyperspectral projection unit to a compressed single pixel camera and Light Labeling (LiLa) technique.
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Mohammad Torabzadeh, Patrick Stockton, Gordon T. Kennedy, Rolf B. Saager, Anthony J. Durkin, Randy A. Bartels, Bruce J. Tromberg, "hyperspectral characterization of tissue simulating phantoms using a supercontinuum laser in a spatial frequency domain imaging instrument", Proc. SPIE 10486, Design and Quality for Biomedical Technologies XI, 104860G (19 February 2018); doi: 10.1117/12.2291369; https://doi.org/10.1117/12.2291369
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