13 February 2018 Biomedical and sensing applications of a multi-mode biodegradable phosphate-based optical fiber
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Abstract
We report on the employment of a biodegradable phosphate-based optical fiber as a pH sensing probe in physiological environment. The phosphate-based optical fiber preform was fabricated by the rod-in-tube technique. The fiber biodegradability was first tested in-vitro and then its biodegradability and toxicity were tested in-vivo. Optical probes for pH sensing were prepared by the immobilization of a fluorescent dye on the fiber tip by a sol-gel method. The fluorescence response of the pH-sensor was measured as a ratio of the emission intensities at the excitation wavelengths of 405 and 450 nm.
Conference Presentation
© (2018) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Ondřej Podrazky, Ondřej Podrazky, Pavel Peterka, Pavel Peterka, Soňa Vytykáčová, Soňa Vytykáčová, Jana Proboštová, Jana Proboštová, Martin Kuneš, Martin Kuneš, Oleksiy Lyutakov, Oleksiy Lyutakov, Edoardo Ceci-Ginistrelli, Edoardo Ceci-Ginistrelli, Diego Pugliese, Diego Pugliese, Nadia G. Boetti, Nadia G. Boetti, Davide Janner, Davide Janner, Daniel Milanese, Daniel Milanese, } "Biomedical and sensing applications of a multi-mode biodegradable phosphate-based optical fiber ", Proc. SPIE 10488, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII, 104880H (13 February 2018); doi: 10.1117/12.2285148; https://doi.org/10.1117/12.2285148
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