A 2.8-mm-diameter scanhead for multispectral photoacoustic microscopy and optical coherence tomography

Zhendong Guo; Jie Wang; Zhongfei Li; Yang Hu; Jigang Wu; Sung-Liang Chen

doi:10.1117/12.2288967

19 February 2018 A 2.8-mm-diameter scanhead for multispectral photoacoustic microscopy and optical coherence tomography

Zhendong Guo, Jie Wang, Zhongfei Li, Yang Hu, Jigang Wu, Sung-Liang Chen

Proceedings Volume 10494, Photons Plus Ultrasound: Imaging and Sensing 2018; 1049456 (2018) https://doi.org/10.1117/12.2288967
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

An endoscopic probe with high resolution and multiple contrasts provides useful diagnostic information. For example, a miniature probe capable of multimodal imaging including photoacoustic imaging, optical coherence tomography (OCT), and ultrasound has been reported. However, microscale resolution is only realized in OCT modality in the probe, which may restrict the applications where high resolutions for multiple contrasts are required. Here, we present an approach to construct a miniature scanhead with 2.8 mm in diameter that achieves high-resolution multispectral photoacoustic microscopy (PAM) and OCT. The method realizes high resolution of ∼10 μm for both PAM and OCT. We experimentally demonstrate ex vivo and in vivo imaging using the scanhead.

Citation Download Citation

Zhendong Guo, Jie Wang, Zhongfei Li, Yang Hu, Jigang Wu, and Sung-Liang Chen "A 2.8-mm-diameter scanhead for multispectral photoacoustic microscopy and optical coherence tomography", Proc. SPIE 10494, Photons Plus Ultrasound: Imaging and Sensing 2018, 1049456 (19 February 2018); https://doi.org/10.1117/12.2288967

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