Novel CuS-based nanoprobes for photoacoustic molecular imaging in the second near-infrared region

Zhen Yuan; Duyang Gao

doi:10.1117/12.2286779

19 February 2018 Novel CuS-based nanoprobes for photoacoustic molecular imaging in the second near-infrared region

Zhen Yuan, Duyang Gao

Proceedings Volume 10494, Photons Plus Ultrasound: Imaging and Sensing 2018; 1049461 (2018) https://doi.org/10.1117/12.2286779
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

In this work, protein-modified hydrophilic copper sufide (CuS) nanotriangles with tunable absorption in the second near-infrared (NIR-II) region are developed, which can be served as contrast agents for enhanced in vivo photoacoustic imaging. In vitro and in vivo toxicity analysis are also performed, which show that the nanoprobes are biocompatible for most of the test cases. As a result, the nanoprones is able to pave a new avenue for improving the photoacoustic imaigng contrast and penetration depth in cancer detection. It should be pointed out that other functional blocks may also be linked on it, which makes it a general method to design multifunctional nanoprobes.

Citation Download Citation

Zhen Yuan and Duyang Gao "Novel CuS-based nanoprobes for photoacoustic molecular imaging in the second near-infrared region", Proc. SPIE 10494, Photons Plus Ultrasound: Imaging and Sensing 2018, 1049461 (19 February 2018); https://doi.org/10.1117/12.2286779

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