19 February 2018 Label-free counting of circulating cells by in vivo photoacoustic flow cytometry
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Proceedings Volume 10495, Biophotonics and Immune Responses XIII; 104950T (2018) https://doi.org/10.1117/12.2289216
Event: SPIE BiOS, 2018, San Francisco, California, United States
Abstract
Melanoma, developing from melanocytes, is the most serious type of skin cancer. Circulating melanoma cells, the prognosis marker for metastasis, are present in the circulation at the early stage. Thus, quantitative detection of rare circulating melanoma cells is essential for monitoring tumor metastasis and prognosis evaluation. Compared with in vitro assays, in vivo flow cytometry is able to identify circulating tumor cells without drawing blood. Here, we built in vivo photoacoustic flow cytometry based on the high absorption coefficient of melanoma cells, which is applied to labelfree counting of circulating melanoma cells in tumor-bearing mice.
© (2018) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Quanyu Zhou, Quanyu Zhou, Ping Yang, Ping Yang, Qiyan Wang, Qiyan Wang, Kai Pang, Kai Pang, Hui Zhou, Hui Zhou, Hao He, Hao He, Xunbin Wei, Xunbin Wei, } "Label-free counting of circulating cells by in vivo photoacoustic flow cytometry", Proc. SPIE 10495, Biophotonics and Immune Responses XIII, 104950T (19 February 2018); doi: 10.1117/12.2289216; https://doi.org/10.1117/12.2289216
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