19 February 2018 A sensor array for detection proteins using lanthanide-doped nanoparticles
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Proceedings Volume 10495, Biophotonics and Immune Responses XIII; 104950V (2018) https://doi.org/10.1117/12.2285921
Event: SPIE BiOS, 2018, San Francisco, California, United States
Abstract
Lanthanide (Ln3+)-doped nanoparticles (NPs) have shown great promise in versatile bioassay. We constructed a supramolecular sensor array by hybridized time-resolved Förster resonance energy transfer (TR-FRET) with the indicator displacement assay (IDA) concept. The sensor array was generated by binding a series of negatively charged indicators on the surface of NaYF4:Ce/Tb NPs. The sensor array could successfully discriminate 6 model proteins with high accuracy and sensitivity both qualitatively and quantitatively.
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Meng Wang, Meng Wang, Benqing Zhou, Benqing Zhou, Feifan Zhou, Feifan Zhou, Junle Qu, Junle Qu, Wei R. Chen, Wei R. Chen, } "A sensor array for detection proteins using lanthanide-doped nanoparticles", Proc. SPIE 10495, Biophotonics and Immune Responses XIII, 104950V (19 February 2018); doi: 10.1117/12.2285921; https://doi.org/10.1117/12.2285921
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