20 February 2018 Improvement of spin-exchange optical pumping of xenon-129 using in situ NMR measurement in ultra-low magnetic field
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Abstract
Hyperpolarized (HP) noble gas has attracted attention in NMR / MRI. In an ultra-low magnetic field, the effectiveness of signal enhancement by HP noble gas should be required because reduction of the signal intensity is serious. One method of generating HP noble gas is spin exchange optical pumping which uses selective excitation of electrons of alkali metal vapor and spin transfer to nuclear spin by collision to noble gas. Although SEOP does not require extreme cooling or strong magnetic field, generally it required large-scale equipment including high power light source to generate HP noble gas with high efficiency. In this study, we construct a simply generation system of HP xenon-129 by SEOP with an ultralow magnetic field (up to 1 mT) and small-scale light source (about 1W). In addition, we measure in situ NMR signal at the same time, and then examine efficient conditions for SEOP in ultra-low magnetic fields.
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Shun Takeda, Shun Takeda, Hiroshi Kumagai, Hiroshi Kumagai, } "Improvement of spin-exchange optical pumping of xenon-129 using in situ NMR measurement in ultra-low magnetic field", Proc. SPIE 10497, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVI, 104971P (20 February 2018); doi: 10.1117/12.2288669; https://doi.org/10.1117/12.2288669
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