23 February 2018 Particle tracking and extended object imaging by interferometric super resolution microscopy
Author Affiliations +
An interferometric fluorescent microscope and a novel theoretic image reconstruction approach were developed and used to obtain super-resolution images of live biological samples and to enable dynamic real time tracking. The tracking utilizes the information stored in the interference pattern of both the illuminating incoherent light and the emitted light. By periodically shifting the interferometer phase and a phase retrieval algorithm we obtain information that allow localization with sub-2 nm axial resolution at 5 Hz.
Conference Presentation
© (2018) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Itay Gdor, Itay Gdor, Seunghwan Yoo, Seunghwan Yoo, Xiaolei Wang, Xiaolei Wang, Matthew Daddysman, Matthew Daddysman, Rosemarie Wilton, Rosemarie Wilton, Nicola Ferrier, Nicola Ferrier, Mark Hereld, Mark Hereld, Oliver (Ollie) Cossairt, Oliver (Ollie) Cossairt, Aggelos Katsaggelos, Aggelos Katsaggelos, Norbert F. Scherer, Norbert F. Scherer, } "Particle tracking and extended object imaging by interferometric super resolution microscopy", Proc. SPIE 10499, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXV, 1049911 (23 February 2018); doi: 10.1117/12.2291245; https://doi.org/10.1117/12.2291245

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