20 February 2018 Ultrasensitive spectroscopy based on photonic waveguides on Al2O3/SiO2 platform
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Here a photonic waveguide on Al2O3/SiO2 platform is proposed to cover the 240~320 nm wavelength-range, which is of paramount significance in protein and nuclei acid quantification. Our optical waveguide increases path-length and overlap integration for light-matter interaction with proteins. The proposed system detects one order less proteins concentration as low as 12.5 μg/ml compared with NanoDropTM that detects <125 μg/ml. Also, a linear absorbance change up to protein concentration of 7500 μg/ml is experimentally attained which is based on the Beer-Lambert-law.
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Elham Heidari, Elham Heidari, Xiaochuan Xu, Xiaochuan Xu, Naimei Tang, Naimei Tang, Farzad Mokhtari-Koushyar, Farzad Mokhtari-Koushyar, Hamed Dalir, Hamed Dalir, Ray T. Chen, Ray T. Chen, } "Ultrasensitive spectroscopy based on photonic waveguides on Al2O3/SiO2 platform", Proc. SPIE 10501, Optical Diagnostics and Sensing XVIII: Toward Point-of-Care Diagnostics, 105011D (20 February 2018); doi: 10.1117/12.2289151; https://doi.org/10.1117/12.2289151

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