CONFERENCE PROCEEDINGS
Advanced Search >
Home > Proceedings > Volume 10502 > Article
Translator Disclaimer
14 March 2018 Image-based adaptive optics compared to wavefront sensing methods for retinal imaging (Conference Presentation)
Daniel J. Wahl; Pengfei Zhang; Yifan Jian; Stefano Bonora; Robert J. Zawadzki; Marinko V. Sarunic
Author Affiliations +
Proceedings Volume 10502, Adaptive Optics and Wavefront Control for Biological Systems IV; 105020G (2018) https://doi.org/10.1117/12.2291244
Event: SPIE BiOS, 2018, San Francisco, California, United States
Abstract
Adaptive Optics (AO) is required to achieve cellular resolution at high numerical aperture in small animal eyes. Development of AO technology is required to lower the barriers of the technology translation into pre-clinical vision research environments. Aberration correction for retinal imaging has been demonstrated with great results by direct wavefront sensor (WFS) measurement. However, in some cases the performance of WFS-based AO can be limited by several factors including common path errors, wavefront reconstruction errors and an ill-defined reference plane on the retina. Image-based AO can avoid these issues and the cost of algorithmic execution time. We are investigating and evaluating image-based approaches to potentially provide improvements to compactness, accessibility, and performance of AO systems. Our experiments were performed on a AO-SLO system which relayed the mouse pupil to a continuous deformable mirror (DM) and Shack-Hartmann wavefront sensor on conjugate planes. The system allows for closed-loop AO as well as the ability measure aberrations during the image-based optimization. We characterized our DM with a WFS in order to use open-loop modal control. The image-based optimization searched the Zernike polynomial coordinate system using a sharpness quality metric. Our results demonstrate diffraction limited performance (according to the WFS) with both closed-loop and image-based methods. The number of iterations required for the image-based method is dependent on the aberrations present as well as the number of dimensions being corrected. Image-based optimization after closed-loop correction can provide further improvements. We are applying these results to improve image-based AO for small animal in-vivo applications.
Conference Presentation
© (2018) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Daniel J. Wahl, Pengfei Zhang, Yifan Jian, Stefano Bonora, Robert J. Zawadzki, and Marinko V. Sarunic "Image-based adaptive optics compared to wavefront sensing methods for retinal imaging (Conference Presentation)", Proc. SPIE 10502, Adaptive Optics and Wavefront Control for Biological Systems IV, 105020G (14 March 2018); doi: 10.1117/12.2291244; https://doi.org/10.1117/12.2291244
ACCESS THE FULL ARTICLE
PERSONAL SIGN IN
Full access may be available with your subscription
 
Forgot your username?
Forgot your password?
No SPIE account? Create an account
Institutional Access:
Sign in with your institutional credentials
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $14.40
Non-members: $18.00 ADD TO CART
PROCEEDINGS
 PRESENTATION ONLY
WATCH
PRESENTATION SAVE TO MY LIBRARY
SHARE
GET CITATION
< Previous Article
|
Next Article >
Advertisement
Advertisement
KEYWORDS
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top