Towards the plasmonic nanopore  for single molecule analysis

Seong Soo Choi; Myoung Jin Park; Sae-Joong Oh; Jung Ho Yoo; Nam Kyou Park; Yong-Sang Kim

doi:10.1117/12.2285908

23 February 2018 Towards the plasmonic nanopore for single molecule analysis

Seong Soo Choi, Myoung Jin Park, Sae-Joong Oh, Jung Ho Yoo, Nam Kyou Park, Yong-Sang Kim

Proceedings Volume 10509, Plasmonics in Biology and Medicine XV; 105090F (2018) https://doi.org/10.1117/12.2285908
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

About sixty years ago, the biological cell counter with an electrical currents detection technique through a micrometer size orifice was invented by Dr. Coulter. A couple of years ago, the ultrafast portable pore device (MinION) with an electrical detection technique was manufactured by Oxford Nanopore Technology. However, high error rates over 80% from this solid state nanopore device is initially reported in several journals. The high error rates may have been contributed from the electrical double layer formed in the pore channel. Even though the error rates have been reduced significantly. Considering the fact that most biosensors are utilizing the optical detection technique, the optical pore device can be an excellent candidate for the next generation single molecule sensor. We will report the fabrication process of the plasmonic optical nanopores.

Citation Download Citation

Seong Soo Choi, Myoung Jin Park, Sae-Joong Oh, Jung Ho Yoo, Nam Kyou Park, and Yong-Sang Kim "Towards the plasmonic nanopore for single molecule analysis", Proc. SPIE 10509, Plasmonics in Biology and Medicine XV, 105090F (23 February 2018); https://doi.org/10.1117/12.2285908

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