20 February 2018 The guided-mode resonance biosensor: principles, technology, and implementation
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The guided-mode resonance (GMR) sensor operates with quasi-guided modes induced in periodic films. The resonance is enabled by 1D or 2D nanopatterns that are expeditiously fabricated. Optical sensors are needed in many fields including medical diagnostics, chemical analyses, and environmental monitoring. Inducing resonance in multiple modes enables extraction of complete bioreaction information including the biolayer thickness, biolayer refractive index, and any change in the refractive index in the background buffer solution. Thus, we refer to this version of the GMR sensor as the complete biosensor. We address the fundamentals, state of technological development, and implementation of this basic sensor modality.
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Robert Magnusson, Robert Magnusson, Kyu J. Lee, Kyu J. Lee, Hafez Hemmati, Hafez Hemmati, Yeong Hwan Ko, Yeong Hwan Ko, Brett R. Wenner, Brett R. Wenner, Jeffery W. Allen, Jeffery W. Allen, Monica S. Allen, Monica S. Allen, Susanne Gimlin, Susanne Gimlin, Debra Wawro Weidanz, Debra Wawro Weidanz, } "The guided-mode resonance biosensor: principles, technology, and implementation", Proc. SPIE 10510, Frontiers in Biological Detection: From Nanosensors to Systems X, 105100G (20 February 2018); doi: 10.1117/12.2288795; https://doi.org/10.1117/12.2288795

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