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9 March 2018 Experimental evaluation of the influence of scattered radiation on quantitative spectral CT imaging
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With the emergence of energy-resolved x-ray photon counting detectors multi-material spectral x-ray imaging has been made possible. This form of imaging allows the discrimination and quantification of individual materials comprising an inspected anatomical area. However, the acquisition of quantitative material data puts strong requirements on the performance capabilities of a given x-ray system. Scattered radiation is one of the key sources of influencing the quality of material quantification accuracy. The aim of the present investigation was to assess the impact of x-ray scatter on quantitative spectral CT imaging using a pre-clinical photon counting scanner prototype. Acquisitions of a cylindrical phantom with and without scatter were performed. The phantom contained iodine and gadolinium inserts placed at various locations. The projection data was then decomposed onto a water-iodine-gadolinium material basis and reconstructed. An analysis of the resulting iodine and gadolinium material images with and without scatter was conducted. It was concluded that, at an SPR level of up to 3.5%, scatter does not compromise material quantification for all investigated gadolinium concentrations, but for iodine a substantial underestimation was observed. The findings in this study suggest that scatter has a lower impact on K-edge material imaging in comparison with material imaging not featuring a K-edge.
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Artur Sossin, Michal Rokni, Bernhard Brendel, Heiner Daerr, Axel Thran, and Klaus Erhard "Experimental evaluation of the influence of scattered radiation on quantitative spectral CT imaging", Proc. SPIE 10573, Medical Imaging 2018: Physics of Medical Imaging, 105731B (9 March 2018);

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