2 March 2018 Microaneurysm detection using deep learning and interleaved freezing
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Abstract
Diabetes affects one in eleven adults. Diabetic retinopathy is a microvascular complication of diabetes and the leading cause of blindness in the working-age population. Microaneurysms are the earliest clinical signs of diabetic retinopathy. This paper proposes an automatic method for detecting microaneurysms in fundus photographies. A novel patch-based fully convolutional neural network for detection of microaneurysms is proposed. Compared to other methods that require five processing stages, it requires only two. Furthermore, a novel network fine-tuning scheme called Interleaved Freezing is presented. This procedure significantly reduces the amount of time needed to re-train a network and produces competitive results. The proposed method was evaluated using publicly available and widely used datasets: E-Ophtha and ROC. It outperforms the state-of-the-art methods in terms of free-response receiver operatic characteristic (FROC) metric. Simplicity, performance, efficiency and robustness of the proposed method demonstrate its suitability for diabetic retinopathy screening applications.
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Piotr Chudzik, Somshubra Majumdar, Francesco Caliva, Bashir Al-Diri, Andrew Hunter, "Microaneurysm detection using deep learning and interleaved freezing", Proc. SPIE 10574, Medical Imaging 2018: Image Processing, 105741I (2 March 2018); doi: 10.1117/12.2293520; https://doi.org/10.1117/12.2293520
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