Tissue imaging using full field optical coherence microscopy with short multimode fiber probe

Manabu Sato; Kai Eto; Tetsuhiro Goto; Reiko Kurotani; Hiroyuki Abe; Izumi Nishidate

doi:10.1117/12.2281404

5 March 2018 Tissue imaging using full field optical coherence microscopy with short multimode fiber probe

Manabu Sato, Kai Eto, Tetsuhiro Goto, Reiko Kurotani, Hiroyuki Abe, Izumi Nishidate

Proceedings Volume 10591, 2nd Canterbury Conference on OCT with Emphasis on Broadband Optical Sources; 1059109 (2018) https://doi.org/10.1117/12.2281404
Event: Second Canterbury Conference on Optical Coherence Tomography, 2017, Canterbury, United Kingdom

Abstract

In achieving minimally invasive accessibility to deeply located regions the size of the imaging probes is important. We demonstrated full-field optical coherence tomography (FF-OCM) using an ultrathin forward-imaging short multimode fiber (SMMF) probe of 50 μm core diameter, 125 μm diameter, and 7.4 mm length for optical communications. The axial resolution was measured to be 2.14 μm and the lateral resolution was also evaluated to be below 4.38 μm using a test pattern (TP). The spatial mode and polarization characteristics of SMMF were evaluated. Inserting SMMF to in vivo rat brain, 3D images were measured and 2D information of nerve fibers was obtained. The feasibility of an SMMF as an ultrathin forward-imaging probe in FF-OCM has been demonstrated.

Citation Download Citation

Manabu Sato, Kai Eto, Tetsuhiro Goto, Reiko Kurotani, Hiroyuki Abe, and Izumi Nishidate "Tissue imaging using full field optical coherence microscopy with short multimode fiber probe", Proc. SPIE 10591, 2nd Canterbury Conference on OCT with Emphasis on Broadband Optical Sources, 1059109 (5 March 2018); https://doi.org/10.1117/12.2281404

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