The recent spread of cheap dermatoscopes for smartphones can empower patients to acquire images of skin lesions on their own and send them to dermatologists. Since images are acquired by different smartphone cameras under unique illumination conditions, the variability in colors is expected. Therefore, the mobile dermatoscopic systems should be calibrated in order to ensure the color constancy in skin images. In this study, we have tested a dermatoscope DermLite DL1 basic, attached to Samsung Galaxy S4 smartphone. Under the controlled conditions, jpeg images of standard color patches were acquired and a model between an unknown device-dependent RGB and a deviceindependent Lab color space has been built. Results showed that median and the best color error was 7.77 and 3.94, respectively. Results are in the range of a human eye detection capability (color error ≈ 4) and video and printing industry standards (color error is expected to be between 5 and 6). It can be concluded that a calibrated smartphone dermatoscope can provide sufficient color constancy and can serve as an interesting opportunity to bring dermatologists closer to the patients.