16 April 2018 Laser nanocomposites based on proteins and carbon nanotubes for restoration of biological tissues
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Proceedings Volume 10614, International Conference on Atomic and Molecular Pulsed Lasers XIII; 106140H (2018) https://doi.org/10.1117/12.2303493
Event: XIII International Conference on Atomic and Molecular Pulsed Lasers, 2017, Tomsk, Russia
Abstract
The study of structural properties of nanocomposites, based on different types of single walled carbon nanotubes (SWCNTs) and proteins (albumin, collagen), was carried out. The binding of protein molecules to the carbon component was described by Raman spectroscopy. Complex analysis of the structure and microporosity of nanocomposites was performed by the X-ray microtomography. The nanoporosity study was carried out using the low-temperature nitrogen porosimetry method. Samples based on SWCNTs with smaller size had the most homogeneity. With an increase in the concentration from 0.01 to 0.1 %, the mean micropore size increased from 45 to 93 μm, porosity in general increased from 16 to 28 %. The percentage of open pores was the same for all samples and was 0.02. As it was shown by Raman spectroscopy the protein component in nanocomposites has undergone irreversible denaturation and can act as a biocompatible binder and serve as a source of amino acids for biological tissues. These nanocomposites are bioresorbable and can be used to repair cartilage and bone tissue. This is especially important in the treatment of diseases of hyaline cartilage and subchondral bone.
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A. Gerasimenko, A. Gerasimenko, U. Kurilova, U. Kurilova, N. Zhurbina, N. Zhurbina, D. Ignatov, D. Ignatov, J. Fedorova, J. Fedorova, P. Privalova, P. Privalova, A. Polokhin, A. Polokhin, D. Ryabkin, D. Ryabkin, M. Savelyev, M. Savelyev, L. Ichkitidze, L. Ichkitidze, V. Podgaetskiy, V. Podgaetskiy, } "Laser nanocomposites based on proteins and carbon nanotubes for restoration of biological tissues", Proc. SPIE 10614, International Conference on Atomic and Molecular Pulsed Lasers XIII, 106140H (16 April 2018); doi: 10.1117/12.2303493; https://doi.org/10.1117/12.2303493
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