12 January 2018 Biocompatibility enhancement of rare earth magnesium alloy by laser surface processing
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Abstract
Although magnesium and magnesium alloys are considered biocompatible and biodegradable, insufficient biocompatibility in body fluid environment is still the major drawback of magnesium alloys for their successful applications as biodegradable orthopaedic implants. In this work, magnesium alloy surface with both enhanced corrosion resistance and better cell adhesion property was directly fabricated by laser surface processing. Laser surface melting was used to improve corrosion resistance of Mg-6Gd-0.6Ca alloy. After laser surface melting, laser surface texturing was utilized on melted surface for better cell adhesion property. The corrosion resistance of laser-treated and as-received samples were evaluated using electrochemical technique. The effect of laser surface treatment on phase and microstructure evolution was evaluated using scanning electron microscopy, optical microscopy and X-ray diffraction. This work investigated the effect of laser treatment on cell distribution across the surface of magnesium alloy substrates. Osteoblast was cultured on the laser-treated surface and as-received surface. Cell morphology was observed with a scanning electron microscopy, and cell viability was evaluated by optical density measurement.
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Shilin Nie, Yuqing Wang, Haifeng Liu, Yingchun Guan, "Biocompatibility enhancement of rare earth magnesium alloy by laser surface processing", Proc. SPIE 10619, 2017 International Conference on Optical Instruments and Technology: Advanced Laser Technology and Applications, 106190B (12 January 2018); doi: 10.1117/12.2291880; https://doi.org/10.1117/12.2291880
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