Designing, operating and maintaining any system in today’s complex Information Technology (IT) environments requires understanding and mitigating various levels of risk to the organization or to individuals associated with the operation of a system. How this risk is managed is critical to the organizations success. Multiple assets, technologies and skilled personnel are needed to select an appropriate set of security controls needed to protect individuals, operations and assets of the organization, and build or refine a security architecture based on best practices and risk management frameworks to adapt to ever changing threats. Developing secure applications and collaborating within a cloud-based environment adds both challenges and mitigations. Cloud environments are scalable and with the proper design and use can be secure and cost-effective. Special attention, processes and techniques associated with authentication and authorization require the formation and maintenance of users, groups, roles and policies. The U.S. Army Research Laboratory (ARL) provides America's Soldiers the technological edge through scientific research, technology development, and analysis. ARL provides scientific and technological innovation in a variety of technical disciplines, through direct in-house laboratory efforts and joint programs with government, industry, and academia. ARL’s Open Campus is a collaborative endeavor, with the goal of building a science and technology ecosystem that will encourage groundbreaking advances in basic and applied research areas of relevance to the Army. Through the Open Campus framework, ARL scientists and engineers work collaboratively and side-by-side with visiting scientists in ARL's facilities, and as visiting researchers at collaborators' institutions. Through the relationships formed and the availability of secure, dynamic and scalable environments, rapid development, sharing and transition of technologies is possible. This technical paper proposes a cloud-based security architecture to support multiple Open Campus Initiatives at the Army Research Laboratory including the Sensor Information Testbed COllaborative Research Environment (SITCORE) and the Automated Online Data Repository (AODR). These initiatives create a highly-collaborative research laboratory and testbed environment focused on sensor data and information fusion. Coupling the existing Open Campus Initiatives with an additional cloud-based architecture allowing encrypted communication, authentication, and on-demand access provides a scalable and secure environment supporting the data, algorithm, and collaborative needs of scientists, researchers and entrepreneurs.