8 August 1989 Model For Thermal Ablation Of Biological Tissue
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Abstract
Assuming that the irradiance of the laser beam is much greater than the threshold for ablation, a simple expression is obtained for the depth of ablation crater as a function of incident fluence. It is expected to be valid even where mechanisms other than thermal dominate the ablation process. A high level of irradiance is necessary to avoid excessive heating of adjacent tissue by heat diffusion. Contrary to expectations based on non-ablative heating, short pulses are not necessarily more effective than longer pulses in minimizing heat diffusion to adjacent tissue. Peripheral heating can further be reduced by using a wavelength with high absorption (short penetration depth) in tissue. Under appropriate conditions of wavelength and irradiance, clean, "cold" cuts are possible with the thermal mechanism of ablation.
© (1989) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
F. Partovi, J A Izatt, M S Feld, S. Strikwerda, J R Kramer, "Model For Thermal Ablation Of Biological Tissue", Proc. SPIE 1064, Thermal and Optical Interactions with Biological and Related Composite Materials, (8 August 1989); doi: 10.1117/12.951945; https://doi.org/10.1117/12.951945
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