Study Of Balloon Laserthermia

Koichi Futatsuki; Koji Saifuku; Kunio Yamamoto; Nobuyuki Takeuchi; Yuzoh Kanda; Toshitaka Uehara; Yoshio Sekiguchi; Norio Daikuzono; Stephen N. Joffe

doi:10.1117/12.952060

11 September 1989 Study Of Balloon Laserthermia

Koichi Futatsuki, Koji Saifuku, Kunio Yamamoto, Nobuyuki Takeuchi, Yuzoh Kanda, Toshitaka Uehara, Yoshio Sekiguchi, Norio Daikuzono, Stephen N. Joffe

Author Affiliations +

Proceedings Volume 1066, Laser Surgery: Advanced Characterization, Therapeutics, and Systems; (1989) https://doi.org/10.1117/12.952060
Event: OE/LASE '89, 1989, Los Angeles, CA, United States

Abstract

A new surgical technique for the Nd:YAG laser, involving irradiation using a balloon filled with a light scattering substance, is described. Applications of this technique to hyperthermia, designated 'balloon laserthermia', were studied. A balloon was attached to the end of the optical fibre, and a substance to scatter the laser light was introduced into the balloon. The laser was activated after the balloon was placed in contact with the tissue. Fat emulsion was used as the scattering substance. From the results of our initial research, it is clear that a 0.25% density of the emulsion is adequate to obtain completely scattered irradiation. The effects of this balloon laserthermia on tumor-bearing mice was investigated pathologically, and more than 90% of the tumor cells in the tumor nodule became necrotic, or showed marked degeneration. As laser hyperthermia becomes possible with this technique over wider areas, we foresee wide clinical applications.

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Koichi Futatsuki, Koji Saifuku, Kunio Yamamoto, Nobuyuki Takeuchi, Yuzoh Kanda, Toshitaka Uehara, Yoshio Sekiguchi, Norio Daikuzono, and Stephen N. Joffe "Study Of Balloon Laserthermia", Proc. SPIE 1066, Laser Surgery: Advanced Characterization, Therapeutics, and Systems, (11 September 1989); https://doi.org/10.1117/12.952060

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